Doctor's Assessment Included

Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.

Hormones

DHEA-S

DHEA-S is the most abundant adrenal hormone and a reliable marker of overall adrenal function. Its age-related decline makes it a valuable indicator for preventive health monitoring.

Reference Ranges

Male

umol/l

Low 2.2 Normal 15.2 High

Female

umol/l

Low 0.9 Normal 11.7 High

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

What It Measures

This test measures the blood concentration of DHEA-S, the sulfated storage form of DHEA. Because DHEA-S levels remain stable throughout the day, it is a reliable indicator of adrenal androgen production.

Why It Matters

Tracking DHEA-S over time provides insight into adrenal ageing and overall hormonal reserve. Early changes may guide preventive lifestyle adjustments. Consult your healthcare provider.

When to Test

Testing may be recommended when evaluating adrenal function, investigating symptoms of androgen excess or deficiency, or assessing age-related hormonal decline.

Symptoms

Low Levels

Some people may experience chronic fatigue, decreased libido, reduced muscle mass, or low mood when DHEA-S levels are below the expected range. These symptoms could suggest adrenal depletion.

High Levels

Some people may experience acne, oily skin, excessive hair growth, or hair thinning when DHEA-S levels are elevated. In women, this could suggest an androgen-related hormonal imbalance.

Recommendations

Male

If Low

Low DHEA-S may indicate adrenal insufficiency or aging. Consider adrenal function testing and lifestyle optimization.

If High

Elevated DHEA-S may indicate adrenal tumors or PCOS. Consult with an endocrinologist for evaluation.

Female

If Low

Low DHEA-S may indicate adrenal insufficiency. Consider comprehensive adrenal evaluation if symptomatic.

If High

High DHEA-S may indicate PCOS or adrenal disorders. Consider PCOS evaluation, especially with irregular periods or hirsutism.

Lifestyle Tips

Adequate sleep, regular moderate exercise, and effective stress management may support healthy DHEA-S production. Avoiding chronic overtraining and ensuring sufficient recovery time could also be beneficial. Discuss supplementation only with your healthcare provider.

Frequently Asked Questions

Does DHEA-S decline with age?

Yes, DHEA-S peaks in early adulthood and declines steadily. Your healthcare provider can assess whether your level is appropriate for your age.

Is DHEA-S the same as DHEA?

DHEA-S is the sulfated storage form of DHEA, with more stable blood levels. It is preferred for testing because it does not fluctuate throughout the day.

Can I supplement DHEA-S?

DHEA supplements are available but should only be used under medical supervision, as they can affect other hormone levels. Consult your healthcare provider first.