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Hormones

DHEA-S Test

DHEA-S is the most abundant adrenal hormone and a reliable marker of overall adrenal function. Its age-related decline makes it a valuable indicator for preventive health monitoring.

Doctor's Assessment Included

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Your reference range
umol/l
0,4 14,2 umol/l
Reference ranges by group, in umol/l
Male · 21–30 years 1–14,2 umol/l
1 14,2
Male · 31–40 years 0,9–11,3 umol/l
0,9 11,3
Male · 41–50 years 0,4–10,6 umol/l
0,4 10,6
Male · 51–60 years < 8,1 umol/l
8,1
Male · 61–70 years < 6,8 umol/l
6,8
Male · 71–80 years < 5,6 umol/l
5,6
Male · 81–90 years < 2,9 umol/l
2,9
Female · 21–30 years 0,6–10,1 umol/l
0,6 10,1
Female · 31–40 years 0,5–7,8 umol/l
0,5 7,8
Female · 41–50 years < 6,2 umol/l
6,2
Female · 51–60 years < 5,8 umol/l
5,8
Female · 61–70 years < 3,5 umol/l
3,5
Female · 71–80 years < 3 umol/l
3
Female · 81–90 years < 2,7 umol/l
2,7
0,4 14,2 umol/l

Referentiewaarden per leeftijdsdecennium en geslacht, zoals gepubliceerd in de labgids van het Maastricht UMC+. Bij de banden die als "< waarde" zijn gepubliceerd (vrouwen vanaf 41 jaar, mannen vanaf 51 jaar) geeft de bron géén ondergrens: een lage uitslag krijgt daarom geen oordeel, want de bron doet er geen uitspraak over. DHEA-S daalt sterk met de leeftijd en is niet cyclusafhankelijk. Er zijn geen banden onder de 21 jaar of boven de 90 jaar. Let op: laboratoria en meetmethoden verschillen aanzienlijk in de referentiewaarden die zij voor DHEA-S hanteren — zowel in de onder- als in de bovengrenzen. Houd daarom altijd de referentiewaarde aan die op uw eigen uitslag staat.

Source: Maastricht UMC+, Centraal Diagnostisch Laboratorium Reference population: MUMC+ labgids (Maastricht UMC+, referentiewaarden DHEA-S)

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

DHEA-S: what this test measures

This test measures the blood concentration of DHEA-S, the sulfated storage form of DHEA. Because DHEA-S levels remain stable throughout the day, it is a reliable indicator of adrenal androgen production.

DHEA-S: why this value matters

Tracking DHEA-S over time provides insight into adrenal ageing and overall hormonal reserve. Early changes may guide preventive lifestyle adjustments. Consult your healthcare provider.

DHEA-S: when is testing worthwhile?

Testing may be recommended when evaluating adrenal function, investigating symptoms of androgen excess or deficiency, or assessing age-related hormonal decline.

DHEA-S: symptoms of a high or low value

Low Levels

Some people may experience chronic fatigue, decreased libido, reduced muscle mass, or low mood when DHEA-S levels are below the expected range. These symptoms could suggest adrenal depletion.

High Levels

Some people may experience acne, oily skin, excessive hair growth, or hair thinning when DHEA-S levels are elevated. In women, this could suggest an androgen-related hormonal imbalance.

DHEA-S: what to do about an abnormal value

Male

If Low

Low DHEA-S may indicate adrenal insufficiency or aging. Consider adrenal function testing and lifestyle optimization.

If High

Elevated DHEA-S may indicate adrenal tumors or PCOS. Consult with an endocrinologist for evaluation.

Female

If Low

Low DHEA-S may indicate adrenal insufficiency. Consider comprehensive adrenal evaluation if symptomatic.

If High

High DHEA-S may indicate PCOS or adrenal disorders. Consider PCOS evaluation, especially with irregular periods or hirsutism.

DHEA-S: lifestyle and this value

Adequate sleep, regular moderate exercise, and effective stress management may support healthy DHEA-S production. Avoiding chronic overtraining and ensuring sufficient recovery time could also be beneficial. Discuss supplementation only with your healthcare provider.

DHEA-S: frequently asked questions

Does DHEA-S decline with age?
Yes, DHEA-S peaks in early adulthood and declines steadily. Your healthcare provider can assess whether your level is appropriate for your age.
Is DHEA-S the same as DHEA?
DHEA-S is the sulfated storage form of DHEA, with more stable blood levels. It is preferred for testing because it does not fluctuate throughout the day.
Can I supplement DHEA-S?
DHEA supplements are available but should only be used under medical supervision, as they can affect other hormone levels. Consult your healthcare provider first.

Test Products

This marker is included in the following test panels.

InsideTracker

InsideTracker

An InsideTracker blood test with 35 biomarkers: heart, hormones, metabolism, inflammation, recovery and iron status. Measured in the Netherlands.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol GGT (Gamma-Glutamyl Transferase) Cortisol DHEA-S Estradiol (E2) Free Testosterone Total Testosterone Folate (Folic Acid) Vitamin B12 Calcium Ferritin Iron (Serum) Magnesium Potassium Progesterone Sodium Transferrin CRP (C-Reactive Protein) Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin AST (Aspartate Aminotransferase) Vitamin D (25-OH) Insulin (Fasting) Leukocyte Differential Creatine Kinase (CK) Transferrin Saturation Triglycerides Basic Blood Count
€399,-
Whoop

Whoop

A 43-biomarker comprehensive health panel inspired by WHOOP Advanced Labs — a deep look at metabolism, cardiovascular risk, hormones, liver, kidney and inflammation.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol Cortisol DHEA-S Estradiol (E2) Free Testosterone FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Total Testosterone Bicarbonate Calcium Chloride Ferritin Iron (Serum) Magnesium Potassium Sodium Transferrin CRP (C-Reactive Protein) Homocysteine Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin HOMA-IR ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) Bilirubin (Total) Total Protein Urea (BUN) Creatinine Vitamin D (25-OH) eGFR (Estimated Glomerular Filtration Rate) Insulin (Fasting) Leukocyte Differential Transferrin Saturation Lipoprotein(a) Triglycerides Basic Blood Count
€499,-
Whoop

Whoop Heart Health

A 45-biomarker heart health panel inspired by the WHOOP Heart Health Panel — an advanced look at cholesterol, lipoproteins, inflammation and kidney function.

Complete Blood Count (CBC) Leukocyte Differential ALP (Alkaline Phosphatase) ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) Albumin Total Protein Bilirubin (Total) ApoB (Apolipoprotein B) Total Cholesterol LDL Cholesterol HDL Cholesterol Triglycerides Lipoprotein(a) Urea (BUN) Creatinine eGFR (Estimated Glomerular Filtration Rate) Calcium Bicarbonate Chloride Sodium Potassium Magnesium Cortisol DHEA-S Estradiol (E2) FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) SHBG (Sex Hormone Binding Globulin) Total Testosterone Free Testosterone TSH (Thyroid Stimulating Hormone) Glucose (Fasting) HbA1c (Glycated Hemoglobin) Insulin (Fasting) HOMA-IR CRP (C-Reactive Protein) Homocysteine Ferritin Iron (Serum) Transferrin Transferrin Saturation Vitamin D (25-OH) Cystatin C Uric Acid
€629,-
Whoop

Whoop Performance Health

A 50-biomarker performance panel inspired by the WHOOP Performance Health Panel — recovery, blood production, thyroid, hormones, iron and nutrient status for people who train.

Complete Blood Count (CBC) Leukocyte Differential ALP (Alkaline Phosphatase) ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) Albumin Total Protein Bilirubin (Total) ApoB (Apolipoprotein B) Total Cholesterol LDL Cholesterol HDL Cholesterol Triglycerides Lipoprotein(a) Urea (BUN) Creatinine eGFR (Estimated Glomerular Filtration Rate) Calcium Bicarbonate Chloride Sodium Potassium Magnesium Cortisol DHEA-S Estradiol (E2) FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) SHBG (Sex Hormone Binding Globulin) Total Testosterone Free Testosterone TSH (Thyroid Stimulating Hormone) Glucose (Fasting) HbA1c (Glycated Hemoglobin) Insulin (Fasting) HOMA-IR CRP (C-Reactive Protein) Homocysteine Ferritin Iron (Serum) Transferrin Transferrin Saturation Vitamin D (25-OH) IGF-1 (Insulin-like Growth Factor) Creatine Kinase (CK) Reticulocytes Free T3 (Triiodothyronine) Free T4 (Thyroxine) Vitamin B12 Folate (Folic Acid)
€689,-
Whoop

Whoop Metabolic Health

A 51-biomarker metabolic panel inspired by the WHOOP Metabolic Health Panel — blood sugar regulation, insulin, thyroid, liver and the mineral cofactors behind your metabolism.

Complete Blood Count (CBC) Leukocyte Differential ALP (Alkaline Phosphatase) ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) Albumin Total Protein Bilirubin (Total) ApoB (Apolipoprotein B) Total Cholesterol LDL Cholesterol HDL Cholesterol Triglycerides Lipoprotein(a) Urea (BUN) Creatinine eGFR (Estimated Glomerular Filtration Rate) Calcium Bicarbonate Chloride Sodium Potassium Magnesium Cortisol DHEA-S Estradiol (E2) FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) SHBG (Sex Hormone Binding Globulin) Total Testosterone Free Testosterone TSH (Thyroid Stimulating Hormone) Glucose (Fasting) HbA1c (Glycated Hemoglobin) Insulin (Fasting) HOMA-IR CRP (C-Reactive Protein) Homocysteine Ferritin Iron (Serum) Transferrin Transferrin Saturation Vitamin D (25-OH) Leptin Zinc Selenium Iodine Copper Free T3 (Triiodothyronine) Free T4 (Thyroxine) GGT (Gamma-Glutamyl Transferase)
€799,-
Whoop

Whoop Women's Health

A 53-biomarker women's health panel inspired by the WHOOP Women's Health Panel — fertility, cycle and thyroid hormones plus a complete metabolic and nutrient base.

Complete Blood Count (CBC) Leukocyte Differential ALP (Alkaline Phosphatase) ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) Albumin Total Protein Bilirubin (Total) ApoB (Apolipoprotein B) Total Cholesterol LDL Cholesterol HDL Cholesterol Triglycerides Lipoprotein(a) Urea (BUN) Creatinine eGFR (Estimated Glomerular Filtration Rate) Calcium Bicarbonate Chloride Sodium Potassium Magnesium Cortisol DHEA-S Estradiol (E2) FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) SHBG (Sex Hormone Binding Globulin) Total Testosterone Free Testosterone TSH (Thyroid Stimulating Hormone) Glucose (Fasting) HbA1c (Glycated Hemoglobin) Insulin (Fasting) HOMA-IR CRP (C-Reactive Protein) Homocysteine Ferritin Iron (Serum) Transferrin Transferrin Saturation Vitamin D (25-OH) AMH (Anti-Müllerian Hormone) Progesterone Prolactin TPO Antibodies Free T3 (Triiodothyronine) Free T4 (Thyroxine) Leptin Vitamin B12 Folate (Folic Acid) Phosphorus
€709,-
Whoop

Whoop Men's Health

A 48-biomarker men's health panel inspired by the WHOOP Men's Health Panel — testosterone, PSA and prostate health plus a complete metabolic and hormone base.

Complete Blood Count (CBC) Leukocyte Differential ALP (Alkaline Phosphatase) ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) Albumin Total Protein Bilirubin (Total) ApoB (Apolipoprotein B) Total Cholesterol LDL Cholesterol HDL Cholesterol Triglycerides Lipoprotein(a) Urea (BUN) Creatinine eGFR (Estimated Glomerular Filtration Rate) Calcium Bicarbonate Chloride Sodium Potassium Magnesium Cortisol DHEA-S Estradiol (E2) FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) SHBG (Sex Hormone Binding Globulin) Total Testosterone Free Testosterone TSH (Thyroid Stimulating Hormone) Glucose (Fasting) HbA1c (Glycated Hemoglobin) Insulin (Fasting) HOMA-IR CRP (C-Reactive Protein) Homocysteine Ferritin Iron (Serum) Transferrin Transferrin Saturation Vitamin D (25-OH) PSA (Prostate-Specific Antigen) Prolactin Leptin Uric Acid Zinc
€659,-

Medical reviewer

Medical standards

Dr. Naimi oversees the medical standards behind our content and assessments.

Medical policy
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DHEA-S

€42,-