Doctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Hepatitis B Core Antibody
A Hepatitis B Core Antibody (anti-HBc) test detects antibodies produced in response to the core antigen of the hepatitis B virus. A positive result may indicate a current, past, or resolved hepatitis B infection and should be interpreted alongside other hepatitis B markers.
What It Measures
This test detects antibodies against the hepatitis B core antigen (HBcAg). These antibodies appear early during infection and can persist for life. The test provides a qualitative result indicating whether anti-HBc antibodies are present, helping to determine exposure history to the hepatitis B virus.
Why It Matters
Anti-HBc is an important marker for determining hepatitis B exposure. It can help distinguish between individuals who have been vaccinated (anti-HBc negative) and those who have been infected (anti-HBc positive). Combined with other hepatitis B markers such as HBsAg and anti-HBs, it supports a comprehensive assessment of hepatitis B status.
When to Test
Testing may be recommended as part of hepatitis B screening, before starting immunosuppressive therapy, during blood donation screening, or when evaluating unexplained liver enzyme elevations. Consult a healthcare professional for guidance on whether this test is appropriate for your situation.
Lifestyle Tips
Support liver health by limiting alcohol consumption, maintaining a healthy weight, and eating a balanced diet. If you have not been vaccinated against hepatitis B, consult your healthcare provider about vaccination. Practise safe hygiene and avoid sharing personal items such as razors or toothbrushes.
Frequently Asked Questions
What does a positive anti-HBc result mean?
A positive anti-HBc result indicates that you have been exposed to the hepatitis B virus at some point. It does not distinguish between a current or past infection on its own. Additional tests such as HBsAg and anti-HBs are needed to determine your current hepatitis B status. Consult a healthcare professional for interpretation.
Can vaccination cause a positive anti-HBc result?
No, hepatitis B vaccination produces anti-HBs antibodies but does not produce anti-HBc antibodies. A positive anti-HBc result indicates natural exposure to the virus rather than vaccine-induced immunity.