Anemia

Anemia refers to a state where the body has fewer red blood cells or less hemoglobin than expected. It can develop for a variety of reasons, including iron deficiency, vitamin deficiencies, or other underlying conditions. Symptoms such as fatigue, weakness, pallor, or shortness of breath may be present, but they are not specific to anemia alone. This panel measures several related markers to help clarify the picture.

This test may be relevant for:

• People experiencing fatigue, pallor, or shortness of breath
• Those who have previously had low hemoglobin and want to investigate further
• Women with heavy menstrual periods who may be at higher risk of iron loss
• Anyone who wants to check whether their iron and blood cell values are within expected ranges

This panel includes:

• CBC (Complete Blood Count): provides information on red blood cells, white blood cells, and platelets
• Hemoglobin: the oxygen-carrying protein in red blood cells; low levels are a hallmark of anemia
• Ferritin: reflects iron stores in the body
• Iron (Serum): the amount of iron currently circulating in the blood
• Transferrin: the protein responsible for transporting iron
• Transferrin Saturation: indicates what percentage of transferrin is carrying iron
• Vitamin B12: involved in red blood cell production; deficiency can lead to a specific type of anemia

Low hemoglobin combined with low ferritin and low transferrin saturation may suggest iron-deficiency anemia. Low Vitamin B12 with changes in red blood cell size (visible in the CBC) could point toward B12-related anemia. Normal iron markers with low hemoglobin may indicate other causes.

The markers work together to provide context. A single low value does not confirm a diagnosis, but a pattern across multiple markers can help guide next steps with a healthcare provider.

This test uses a blood sample collected at a certified sample point (afnamepunt). With over 750 partner locations across the Netherlands, you can choose a location that works for you. A trained phlebotomist performs the blood draw, and results are typically available within a few working days.

This test may be useful when:

• You experience symptoms that could be associated with anemia, such as persistent tiredness or feeling light-headed
• You have been told you have low hemoglobin and want to understand the cause
• You have risk factors for iron loss, such as heavy periods or a diet low in iron
• You want to check your iron and B12 status alongside your blood cell values

Each marker is shown with your value and the reference range. Hemoglobin below the reference range may suggest anemia, but the type and cause depend on the pattern of the other markers. For example, small red blood cells with low ferritin suggest a different cause than large red blood cells with low B12.

Your report provides explanations for each marker. We recommend discussing the results with a healthcare provider, who can assess the overall pattern and advise on any appropriate follow-up.

Fasting is not strictly required but may improve the accuracy of serum iron measurements. If you choose to fast, 8 to 12 hours is recommended. Avoid iron supplements for at least 24 hours before the test, as they can temporarily affect iron-related values.

Your results are typically available within a few working days. The report includes your values with reference ranges and plain-language explanations. If any markers fall outside the expected range, this is clearly indicated. We recommend reviewing the results with a healthcare provider, who can interpret the pattern and advise on next steps if needed.