Insulin Resistance (HOMA-IR)
A focused look at insulin resistance from fasting glucose and insulin, with your HOMA-IR score.
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Included Markers
3 markersHOMA-IR (Homeostatic Model Assessment of Insulin Resistance) estimates insulin resistance from a fasting blood sample. It is a simple, well-established way of tracking your overall metabolic health and catching insulin resistance early.
What is HOMA-IR?
HOMA-IR is a calculated score, not a separate measurement. It is derived from two fasting markers: fasting glucose and fasting insulin, using the formula (glucose × insulin) / 22.5. A higher score points towards more insulin resistance; a lower score towards better insulin sensitivity.
Why this test?
Insulin resistance often develops quietly. Fasting insulin can rise to keep glucose normal long before fasting glucose itself moves, so HOMA-IR can surface metabolic change earlier than a glucose test alone. This panel is aimed at tracking your overall metabolic health and catching insulin resistance early.
What is tested?
The panel measures and reports three things:
- Glucose (fasting) — your fasting blood sugar
- Insulin (fasting) — the hormone that moves glucose into cells
- HOMA-IR — the calculated insulin-resistance score from the two values above
How is the sample collected?
The test is a blood draw at a certified sample point (afnamepunt), with over 750 locations across the Netherlands. After ordering, you choose a convenient location and plan your visit. The draw is performed by trained professionals.
Preparation — fasting required
Both glucose and insulin must be measured fasting, so this test requires fasting. Do not eat or drink anything except water for 8 to 12 hours before the blood draw, and avoid alcohol the evening before. Take your blood drawn in the morning where possible.
What happens after the results?
Results are usually available within a few working days. Glucose and insulin are shown with their reference ranges, and HOMA-IR with its interpretation band. These are intended to be discussed with your doctor, who can interpret them in the context of your personal situation.
Frequently Asked Questions
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Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your results and writes a personal report. On your dashboard within a few business days.
Choose your blood test
Browse our blood tests and pick what you want checked. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your results and writes a personal report. On your dashboard within a few business days.
Always a location near you
With more than 650+ certified phlebotomy points across the Netherlands.
What We Test
This health panel includes 3 biomarkers to give you a comprehensive picture of your health.
Fasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes.
Learn moreFasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal.
Learn moreHOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a calculated index derived from fasting glucose and fasting insulin levels. It is widely used to estimate insulin resistance, a condition where the body's cells respond less effectively to insulin.
Learn moreGlucose (Fasting)
MetabolicFasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes.
Fasting glucose is a cornerstone of metabolic health assessment. Elevated levels may indicate pre-diabetes or diabetes, while very low levels can also be clinically significant. Consult your healthcare provider for interpretation.
Insulin (Fasting)
MetabolicFasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal.
Fasting insulin can detect insulin resistance years before diabetes develops. Early detection allows for lifestyle interventions that may prevent progression. Consult your healthcare provider for personalised advice.
HOMA-IR
MetabolicHOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a calculated index derived from fasting glucose and fasting insulin levels. It is widely used to estimate insulin resistance, a condition where the body's cells respond less effectively to insulin.
Insulin resistance is often linked to an increased risk of type 2 diabetes, metabolic syndrome, cardiovascular disease, and other metabolic conditions. HOMA-IR can help identify insulin resistance in its early stages, when lifestyle interventions may be most effective.
Related biomarkers
Biomarkers often explored alongside this test for a fuller picture.
C-Peptide
C-Peptide provides early insight into pancreatic function and insulin resistance. Proactive testing supports early detection of metabolic changes before diabetes develops.
HbA1c (Glycated Hemoglobin)
HbA1c is the gold standard for assessing diabetes risk and long-term metabolic health. Regular monitoring is essential for proactive prevention.
Lactate
Resting lactate levels can indicate metabolic efficiency and tissue oxygenation. Including this marker supports a thorough metabolic health assessment.
Uric Acid
Uric acid is a valuable metabolic marker for gout, kidney stone, and cardiovascular risk. Proactive monitoring supports early intervention and prevention.
Related Health Panels
Discover more panels for a comprehensive health picture.
Complete Metabolic Panel
Comprehensive metabolic panel: electrolytes, kidney, liver, glucose, HbA1c, and protein.
Lipids
LDL, HDL, and Triglycerides: your cardiovascular risk markers.
Diabetes
Fasting glucose and HbA1c: screen for prediabetes.
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