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Hormones

ACTH Blood Test

ACTH is a pituitary hormone that controls cortisol production by your adrenal glands. Monitoring ACTH levels as part of your health routine may help provide early insights into how well your stress response system is functioning.

Doctor's Assessment Included

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Male Your group
pmol/l
Low 1.6 Normal 13.9 High
Female Your group
pmol/l
Low 1.6 Normal 13.9 High

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

ACTH (Adrenocorticotropic Hormone): what this test measures

This test measures the level of ACTH in your blood. Results may help evaluate how well your pituitary gland communicates with your adrenal glands to regulate cortisol production and maintain hormonal balance throughout the day.

ACTH (Adrenocorticotropic Hormone): why this value matters

Tracking ACTH levels may help identify early signs of pituitary or adrenal imbalance before symptoms become pronounced. Understanding your baseline could support proactive health decisions. Your healthcare provider can guide you through the results.

ACTH (Adrenocorticotropic Hormone): how the blood test works

Referral
No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw
A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Which test
on its own €49,-
Where
650+ draw sites run by independent laboratories across the Netherlands. Draw sites

ACTH (Adrenocorticotropic Hormone): how to prepare

  1. Pause biotin

    Required

    Do you take a supplement with biotin (vitamin B8, common in hair, skin and nail supplements)? Stop it 72 hours before the draw. Biotin interferes with the measurement of these values.

  2. Have the draw in the morning

    Required

    These values vary over the day and peak in the morning. Have your blood drawn before 10:00, ideally between 07:00 and 09:00.

  • Water is always fine. Drink as usual beforehand, it makes the draw easier.
  • Take your usual medication, unless your own doctor told you otherwise.

ACTH (Adrenocorticotropic Hormone): when is testing worthwhile?

ACTH testing is typically recommended in the early morning, when levels are naturally at their peak. Your healthcare provider may suggest this test if you show signs of adrenal or pituitary dysfunction, or unexplained fatigue.

ACTH (Adrenocorticotropic Hormone): symptoms of a high or low value

Low Levels

Some people may experience fatigue, muscle weakness, weight loss, or low blood pressure when ACTH levels are below the expected range. These symptoms could suggest reduced adrenal stimulation. A healthcare provider can help determine the underlying cause.

High Levels

Some people may experience weight gain, skin changes, high blood pressure, or mood disturbances when ACTH levels are elevated. High levels could suggest overstimulation of the adrenal glands. Discuss your results with your healthcare provider.

ACTH (Adrenocorticotropic Hormone): lifestyle and this value

Maintaining a consistent sleep schedule, managing stress through mindfulness or exercise, and eating a nutrient-rich diet may support healthy pituitary-adrenal function. Avoid excessive caffeine and alcohol. Always consult your healthcare provider for personalized advice.

ACTH (Adrenocorticotropic Hormone): frequently asked questions

What does ACTH do?

ACTH signals your adrenal glands to produce cortisol, helping regulate your body's stress response.

Why is morning testing preferred?

ACTH levels follow a daily rhythm and are typically highest in the early morning hours.

Can stress affect ACTH levels?

Yes, physical or emotional stress may temporarily increase ACTH production from the pituitary gland.

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Medical reviewer

Medical standards

Dr. Naimi oversees the medical standards behind our content and assessments.

Medical policy
CIBG Ministerie van Volksgezondheid,
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ACTH (Adrenocorticotropic Hormone)

€49,-