ANA is the first-line autoimmune screening test. Including it in a comprehensive panel helps identify autoimmune conditions early, when treatment is most effective.
Doctor's Assessment Included
This test detects autoantibodies against nuclear antigens using immunofluorescence or immunoassay. Results include titre (dilution level) and pattern (homogeneous, speckled, nucleolar, centromere), which help guide further testing.
ANA is the first-line screening test for systemic autoimmune diseases. While a negative ANA largely excludes SLE, a positive ANA alone does not diagnose any specific condition and requires clinical correlation.
Testing could be indicated for suspected autoimmune disease: joint pain, skin rashes, unexplained fatigue, Raynaud phenomenon, or organ involvement without clear cause.
A negative ANA makes systemic lupus and many other autoimmune conditions unlikely but does not completely exclude all autoimmune diseases.
A positive ANA can be associated with SLE, Sjogren syndrome, scleroderma, mixed connective tissue disease, and other conditions. However, up to 15% of healthy people have low-titre positive ANA.
If ANA is positive with symptoms, consult a rheumatologist for further evaluation. Manage stress, protect skin from sun exposure (UV can trigger lupus flares), and maintain regular follow-up appointments.
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Medical policyDoctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
ANA (Antinuclear Antibodies)
€39,-
