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Coagulation

Protein C Activity

Protein C Activity testing evaluates a critical component of your natural anticoagulant system. Proactive screening identifies deficiency before a thrombotic event occurs.

Doctor's Assessment Included

Protein C (Activity): what this test measures

This test measures the functional anticoagulant activity of Protein C, expressed as a percentage of normal.

Protein C (Activity): why this value matters

Protein C deficiency, whether inherited or acquired, is an important cause of thrombophilia. Early identification allows preventive measures during high-risk situations.

Protein C (Activity): when is testing worthwhile?

Testing could be indicated for unexplained venous thrombosis, family history of Protein C deficiency, or as part of thrombophilia screening. Avoid testing on warfarin as it suppresses Protein C.

Protein C (Activity): symptoms of a high or low value

Low Levels

Low Protein C activity increases thrombosis risk. In adults, symptoms relate to thrombotic events (DVT, PE) rather than the deficiency itself.

High Levels

Elevated Protein C activity is generally not clinically significant and does not require intervention.

Protein C (Activity): lifestyle and this value

If Protein C deficiency is confirmed, reduce thrombosis risk factors, discuss anticoagulation for high-risk situations, and inform family members who may benefit from testing.

Protein C (Activity): frequently asked questions

How common is Protein C deficiency?
Inherited Protein C deficiency affects about 1 in 200-500 people. Most are heterozygous with moderately reduced levels.
Why avoid testing on warfarin?
Warfarin suppresses vitamin K-dependent proteins including Protein C, giving falsely low results.
Is Protein C related to Protein S?
Yes. Protein S is a cofactor for Protein C. Both are vitamin K-dependent natural anticoagulants.

Tests with related values

These panels measure values from the same category as this marker.

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Medical standards

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Medical policy
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Protein C (Activity)

€89,-