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Digoxin

Digoxin monitoring is a vital component of managing your prescribed heart medication. Due to its narrow therapeutic window, regular blood level checks are essential to ensure your treatment remains both safe and effective.

Doctor's Assessment Included

When is this value abnormal?

Decision limits per result, in ug/l
Result Value (ug/l)
Subtherapeutic < 0,8
Therapeutic 0,8–2
Above therapeutic range ≥ 2

Dalspiegel. Bereik voor atriumfibrilleren; bij hartfalen geldt een lagere streefwaarde van 0,5–0,9 µg/l. Toxisch: > 2,0 µg/l.

Source: UMC Utrecht

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

What It Measures

This test measures the concentration of digoxin in your blood. It ensures that the dose prescribed by your doctor maintains therapeutic levels to effectively manage your heart condition while minimising the risk of toxicity.

Why It Matters

Digoxin has one of the narrowest therapeutic windows of any medication. The difference between an effective and a toxic dose is small. Levels that are too low may not adequately control your heart condition, while even slightly elevated levels can be associated with serious and potentially life-threatening side effects.

When to Test

Your doctor may request this test when starting digoxin, after dose adjustments, when kidney function changes, if toxicity symptoms appear, or when other medications are added that may interact with digoxin. Regular monitoring is standard practice during ongoing treatment.

Symptoms

Low Levels

Levels below the therapeutic range may indicate subtherapeutic dosing, meaning the medication may not be providing adequate control of your heart condition. This can be associated with worsening heart failure symptoms or return of arrhythmia. Consult a healthcare professional for interpretation of results.

High Levels

Levels above the therapeutic range may indicate a risk of digoxin toxicity. Symptoms can include nausea, vomiting, visual disturbances (such as yellow-green vision or halos), confusion, and dangerous cardiac arrhythmias. Contact your doctor immediately if you experience these symptoms. Consult a healthcare professional for interpretation of results.

Lifestyle Tips

Take digoxin exactly as prescribed by your doctor. Maintain consistent potassium levels through a balanced diet, as low potassium can increase digoxin sensitivity. Inform your doctor of all other medications and supplements, especially diuretics. Do not adjust your dose without medical guidance.

Frequently Asked Questions

Why is digoxin monitoring so important?
Digoxin has a very narrow therapeutic window, meaning the margin between an effective dose and a toxic dose is small. Regular monitoring helps your doctor keep your levels in the safe and effective range.
Can potassium levels affect digoxin safety?
Yes, low potassium levels (hypokalaemia) can increase your sensitivity to digoxin, raising the risk of toxicity even when digoxin levels appear to be within range. Your doctor may monitor your potassium levels alongside digoxin.
What should I do if I suspect digoxin toxicity?
If you experience nausea, vision changes, confusion, or an irregular heartbeat while taking digoxin, contact your doctor or seek medical attention immediately. Do not stop taking the medication without medical advice, but prompt evaluation is essential.

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These panels measure values from the same category as this marker.

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SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol Cortisol DHEA-S Estradiol (E2) Free Testosterone FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Total Testosterone Bicarbonate Calcium Chloride Ferritin Iron (Serum) Magnesium Potassium Sodium Transferrin CRP (C-Reactive Protein) Homocysteine Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Omega-3 Index Total Cholesterol Albumin HOMA-IR ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) Bilirubin (Total) Total Protein Urea (BUN) Creatinine Vitamin D (25-OH) eGFR (Estimated Glomerular Filtration Rate) Insulin (Fasting) Leukocyte Differential Transferrin Saturation Lipoprotein(a) Triglycerides Basic Blood Count
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Digoxin

€49,-