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Coagulation

Lupus Anticoagulant Test

Lupus anticoagulant testing identifies one of the strongest predictors of thrombosis. Including it in a comprehensive screen provides critical clotting risk information.

Doctor's Assessment Included

Reference Ranges

Expected result Negative

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

Lupus Anticoagulant: what this test measures

This test detects the presence of lupus anticoagulant antibodies through a series of phospholipid-dependent clotting assays. It is reported as positive or negative, not as a quantitative level.

Lupus Anticoagulant: why this value matters

Lupus anticoagulant is the strongest predictor of thrombosis among the antiphospholipid antibodies. Persistent positivity (confirmed at 12+ weeks) is required for APS diagnosis.

Lupus Anticoagulant: how the blood test works

Referral
No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw
A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Which test
on its own €98,-
Where
650+ draw sites run by independent laboratories across the Netherlands. Draw sites

Lupus Anticoagulant: when is testing worthwhile?

Testing could be indicated for unexplained thrombosis, recurrent pregnancy loss, unexplained prolonged aPTT, or suspected antiphospholipid syndrome.

Lupus Anticoagulant: symptoms of a high or low value

Low Levels

A negative result means lupus anticoagulant was not detected, which is normal and does not require follow-up.

High Levels

A positive lupus anticoagulant is associated with increased risk of venous and arterial thrombosis, stroke, and pregnancy complications including recurrent miscarriage and pre-eclampsia.

Lupus Anticoagulant: lifestyle and this value

If lupus anticoagulant is persistently positive, discuss long-term anticoagulation with your healthcare provider. Reduce modifiable thrombosis risk factors and avoid oestrogen-containing contraception.

Lupus Anticoagulant: frequently asked questions

Does lupus anticoagulant mean I have lupus?

No. Despite its name, lupus anticoagulant can occur in people without lupus. It is found in antiphospholipid syndrome, other autoimmune conditions, and sometimes in healthy individuals.

Why does it cause clotting if it is called an anticoagulant?

The name is misleading. It prolongs clotting in laboratory tests but promotes clotting in the body. This paradox is a key feature of antiphospholipid antibodies.

How many times must it be positive for diagnosis?

Antiphospholipid syndrome requires persistent positivity confirmed on two occasions at least 12 weeks apart.

Tests with related values

These panels measure values from the same category as this marker.

Medical reviewer

Medical standards

Dr. Naimi oversees the medical standards behind our content and assessments.

Medical policy
CIBG Ministerie van Volksgezondheid,
Welzijn en Sport Official BIG registration BIG 49928676701 Opens in a new tab

Lupus Anticoagulant

€98,-