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Cardiovascular

NT-proBNP

NT-proBNP is one of the most sensitive markers for heart failure screening. Proactive testing supports early detection and cardiac health management.

Doctor's Assessment Included

When is this value abnormal?

Decision limits per result, in pmol/l
Result Value (pmol/l)
Normal < 15
Elevated ≥ 15

Dit is een afkapwaarde, geen referentiewaarde: de NHG-Standaard Hartfalen schrijft voor deze grens te gebruiken, ook als het laboratorium andere referentiewaarden vermeldt. Geldt voor geleidelijk ontstane (niet-acute) klachten. Let op: bij atriumfibrilleren sluit een waarde ónder de afkapwaarde hartfalen niet uit. Een NT-proBNP kan verlaagd zijn bij overgewicht en bij gebruik van hartfalenmedicatie, en verhoogd bij nierschade, atriumfibrilleren, hogere leeftijd en ernstige infectie.

Source: Nederlands Huisartsen Genootschap Reference population: Volwassenen met vermoeden van hartfalen (NHG-Standaard Hartfalen)

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

What It Measures

This test measures the level of NT-proBNP in your blood. Higher levels indicate greater cardiac stress and may suggest heart failure or other cardiac conditions.

Why It Matters

NT-proBNP is one of the best biomarkers for detecting heart failure and monitoring its severity. It can also help distinguish cardiac from non-cardiac causes of shortness of breath. Consult your healthcare provider.

When to Test

Testing may be recommended if you experience shortness of breath, fatigue, swelling in the legs, or other symptoms suggestive of heart failure.

Symptoms

Low Levels

Low NT-proBNP levels generally rule out significant heart failure and indicate normal cardiac wall stress.

High Levels

Elevated NT-proBNP may be associated with heart failure, atrial fibrillation, pulmonary embolism, or other conditions that stress the heart. Symptoms may include breathlessness, fatigue, and fluid retention.

Lifestyle Tips

Maintain cardiovascular health through regular exercise, a balanced diet, blood pressure management, and stress reduction. If you have heart failure, follow your healthcare provider's treatment plan carefully.

Frequently Asked Questions

Can NT-proBNP diagnose heart failure?
NT-proBNP is a powerful tool for detecting heart failure, but diagnosis requires clinical evaluation alongside other tests. Low levels make heart failure unlikely.
Does age affect NT-proBNP?
Yes, NT-proBNP levels naturally increase with age. Your healthcare provider will use age-appropriate reference ranges for interpretation.
Can exercise affect NT-proBNP?
Intense exercise can temporarily elevate NT-proBNP. This is usually not a concern in healthy individuals but should be discussed with your healthcare provider if persistent.

Tests with related values

These panels measure values from the same category as this marker.

Whoop

A 44-biomarker comprehensive health panel inspired by WHOOP Advanced Labs — a deep look at metabolism, cardiovascular risk, hormones, liver, kidney and inflammation.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol Cortisol DHEA-S Estradiol (E2) Free Testosterone FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Total Testosterone Bicarbonate Calcium Chloride Ferritin Iron (Serum) Magnesium Potassium Sodium Transferrin CRP (C-Reactive Protein) Homocysteine Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Omega-3 Index Total Cholesterol Albumin HOMA-IR ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) Bilirubin (Total) Total Protein Urea (BUN) Creatinine Vitamin D (25-OH) eGFR (Estimated Glomerular Filtration Rate) Insulin (Fasting) Leukocyte Differential Transferrin Saturation Lipoprotein(a) Triglycerides Basic Blood Count
€499,-

InsideTracker

A 36-biomarker performance and longevity panel inspired by InsideTracker Ultimate — covering heart, hormones, metabolism, inflammation, recovery and iron status.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol GGT (Gamma-Glutamyl Transferase) Cortisol DHEA-S Estradiol (E2) Free Testosterone Total Testosterone Folate (Folic Acid) Vitamin B12 Calcium Ferritin Iron (Serum) Magnesium Magnesium (Intracellular) Potassium Progesterone Sodium Transferrin CRP (C-Reactive Protein) Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin AST (Aspartate Aminotransferase) Vitamin D (25-OH) Insulin (Fasting) Leukocyte Differential Creatine Kinase (CK) Transferrin Saturation Triglycerides Basic Blood Count
€399,-

NT-proBNP

€82,-