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Hematology

Haptoglobin

A haptoglobin test measures the level of haptoglobin protein in your blood. Haptoglobin binds to free hemoglobin released from damaged red blood cells, and its levels can help assess whether red blood cells are being destroyed faster than normal.

Doctor's Assessment Included

What It Measures

This test measures the concentration of haptoglobin in your blood serum. Haptoglobin is a protein produced by the liver that captures free hemoglobin released during the normal or accelerated breakdown of red blood cells, preventing kidney damage from free hemoglobin.

Why It Matters

Low haptoglobin levels may indicate hemolytic anemia, a condition where red blood cells are destroyed prematurely. This test is valuable in distinguishing between different types of anemia and identifying conditions that cause increased red blood cell destruction.

When to Test

Testing may be recommended when hemolytic anemia is suspected, when investigating unexplained anemia, or as a follow-up to abnormal results on other blood tests such as a complete blood count. Consult a healthcare professional for interpretation of results.

Symptoms

Low Levels

Low haptoglobin may be associated with hemolytic anemia symptoms: fatigue, weakness, pale or yellow skin, dark urine, rapid heartbeat, shortness of breath.

High Levels

Elevated haptoglobin may be associated with inflammation, infection, tissue damage, or certain chronic conditions. Symptoms depend on the underlying cause.

Lifestyle Tips

Maintain a balanced diet with adequate iron and B vitamins to support red blood cell health. Stay hydrated and avoid exposure to substances known to damage red blood cells. If you experience symptoms of anemia, seek medical evaluation promptly.

Frequently Asked Questions

What does a low haptoglobin level mean?
A low haptoglobin level may indicate that red blood cells are being destroyed at a faster rate than normal, a process known as hemolysis. This can be associated with various conditions including autoimmune disorders, infections, or inherited blood conditions. Your healthcare provider will interpret the result in context.
Can haptoglobin levels be affected by other conditions?
Yes, haptoglobin is also an acute-phase protein, meaning its levels can rise during inflammation, infection, or tissue injury. This is why results are often interpreted alongside other blood tests for a comprehensive picture.

Tests with related values

These panels measure values from the same category as this marker.

InsideTracker

A 36-biomarker performance and longevity panel inspired by InsideTracker Ultimate — covering heart, hormones, metabolism, inflammation, recovery and iron status.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol GGT (Gamma-Glutamyl Transferase) Cortisol DHEA-S Estradiol (E2) Free Testosterone Total Testosterone Folate (Folic Acid) Vitamin B12 Calcium Ferritin Iron (Serum) Magnesium Magnesium (Intracellular) Potassium Progesterone Sodium Transferrin CRP (C-Reactive Protein) Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin AST (Aspartate Aminotransferase) Vitamin D (25-OH) Insulin (Fasting) Leukocyte Differential Creatine Kinase (CK) Transferrin Saturation Triglycerides Basic Blood Count
€399,-

Whoop

A 44-biomarker comprehensive health panel inspired by WHOOP Advanced Labs — a deep look at metabolism, cardiovascular risk, hormones, liver, kidney and inflammation.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol Cortisol DHEA-S Estradiol (E2) Free Testosterone FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Total Testosterone Bicarbonate Calcium Chloride Ferritin Iron (Serum) Magnesium Potassium Sodium Transferrin CRP (C-Reactive Protein) Homocysteine Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Omega-3 Index Total Cholesterol Albumin HOMA-IR ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) Bilirubin (Total) Total Protein Urea (BUN) Creatinine Vitamin D (25-OH) eGFR (Estimated Glomerular Filtration Rate) Insulin (Fasting) Leukocyte Differential Transferrin Saturation Lipoprotein(a) Triglycerides Basic Blood Count
€499,-

Haptoglobin

€33,-