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Hematology

Hemoglobin Electrophoresis

Hemoglobin electrophoresis is a laboratory technique that separates and identifies different types of hemoglobin in your blood. It is primarily used to detect hemoglobin variants and diagnose inherited blood disorders such as sickle cell disease and thalassemia.

Doctor's Assessment Included

Reference Ranges

No established reference range

A haemoglobin electrophoresis does not produce a single number but a pattern of fractions (HbA, HbA2, HbF and any variants such as HbS or HbC). One reference interval for the test as a whole cannot be interpreted: a clinically important raised HbA2 — the marker of beta-thalassaemia carriership — would be wrongly reported as "low". The result is assessed per fraction.

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Hemoglobin Electrophoresis: what this test measures

This test separates the different types of hemoglobin present in your blood based on their electrical charge and size. It identifies the proportions of normal hemoglobin (HbA, HbA2, HbF) and detects abnormal variants such as HbS (sickle hemoglobin) or HbC.

Hemoglobin Electrophoresis: why this value matters

Identifying hemoglobin variants is important for diagnosing conditions such as sickle cell disease, thalassemia, and other hemoglobinopathies. Early detection allows for appropriate management, genetic counselling, and informed family planning decisions.

Hemoglobin Electrophoresis: when is testing worthwhile?

Testing may be recommended as part of newborn screening, when a hemoglobin disorder is suspected based on symptoms or family history, or before planned anaesthesia. It may also be suggested for individuals from populations with higher prevalence of hemoglobin disorders.

Hemoglobin Electrophoresis: lifestyle and this value

If you carry a hemoglobin variant, share this information with your healthcare providers. Consider genetic counselling if planning a family, especially if both partners carry a trait. Stay informed about your specific variant and follow recommended screening schedules.

Hemoglobin Electrophoresis: frequently asked questions

What is the difference between having a trait and having the disease?
Carrying a trait (such as sickle cell trait) means you have one copy of the variant gene and typically do not have symptoms. Having the disease means you have two copies, which can cause significant health effects. A healthcare provider or genetic counsellor can explain your specific results.
Should my family members be tested?
If a hemoglobin variant is detected, it may be recommended that close family members also undergo testing. This is especially relevant for siblings, children, and partners who may be planning a family together. Consult a healthcare professional for guidance.

Tests with related values

These panels measure values from the same category as this marker.

Whoop

Whoop Performance Health

A 50-biomarker performance panel inspired by the WHOOP Performance Health Panel — recovery, blood production, thyroid, hormones, iron and nutrient status for people who train.

Complete Blood Count (CBC) Leukocyte Differential ALP (Alkaline Phosphatase) ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) Albumin Total Protein Bilirubin (Total) ApoB (Apolipoprotein B) Total Cholesterol LDL Cholesterol HDL Cholesterol Triglycerides Lipoprotein(a) Urea (BUN) Creatinine eGFR (Estimated Glomerular Filtration Rate) Calcium Bicarbonate Chloride Sodium Potassium Magnesium Cortisol DHEA-S Estradiol (E2) FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) SHBG (Sex Hormone Binding Globulin) Total Testosterone Free Testosterone TSH (Thyroid Stimulating Hormone) Glucose (Fasting) HbA1c (Glycated Hemoglobin) Insulin (Fasting) HOMA-IR CRP (C-Reactive Protein) Homocysteine Ferritin Iron (Serum) Transferrin Transferrin Saturation Vitamin D (25-OH) IGF-1 (Insulin-like Growth Factor) Creatine Kinase (CK) Reticulocytes Free T3 (Triiodothyronine) Free T4 (Thyroxine) Vitamin B12 Folate (Folic Acid)
€689,-
Whoop

Whoop

A 43-biomarker comprehensive health panel inspired by WHOOP Advanced Labs — a deep look at metabolism, cardiovascular risk, hormones, liver, kidney and inflammation.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol Cortisol DHEA-S Estradiol (E2) Free Testosterone FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Total Testosterone Bicarbonate Calcium Chloride Ferritin Iron (Serum) Magnesium Potassium Sodium Transferrin CRP (C-Reactive Protein) Homocysteine Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin HOMA-IR ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) Bilirubin (Total) Total Protein Urea (BUN) Creatinine Vitamin D (25-OH) eGFR (Estimated Glomerular Filtration Rate) Insulin (Fasting) Leukocyte Differential Transferrin Saturation Lipoprotein(a) Triglycerides Basic Blood Count
€499,-
InsideTracker

InsideTracker

An InsideTracker blood test with 35 biomarkers: heart, hormones, metabolism, inflammation, recovery and iron status. Measured in the Netherlands.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol GGT (Gamma-Glutamyl Transferase) Cortisol DHEA-S Estradiol (E2) Free Testosterone Total Testosterone Folate (Folic Acid) Vitamin B12 Calcium Ferritin Iron (Serum) Magnesium Potassium Progesterone Sodium Transferrin CRP (C-Reactive Protein) Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin AST (Aspartate Aminotransferase) Vitamin D (25-OH) Insulin (Fasting) Leukocyte Differential Creatine Kinase (CK) Transferrin Saturation Triglycerides Basic Blood Count
€399,-

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Medical standards

Dr. Naimi oversees the medical standards behind our content and assessments.

Medical policy
CIBG Ministerie van Volksgezondheid,
Welzijn en Sport Official BIG registration BIG 49928676701 Opens in a new tab

Hemoglobin Electrophoresis

€81,-